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Blood Profile of Rabbits Infected with Eimeria magna


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Title Statement Blood Profile of Rabbits Infected with Eimeria magna
Added Entry - Uncontrolled Name Hana, A
Salasia, SIO
Mangkoewidjojo, S
Kusindarto, DL
Summary, etc. <p><strong>Abstract</strong><strong>. </strong>The research aimed at determining the blood profile of local rabbits infected with different dose of <em>Eimeria</em><em> magna</em> oocysts. This research used 45 male rabbits with the age of 4 month old, range from 1.5 to 1.8 kg, clinically healthy and free from coccidiosis. The rabbits were randomly divided into 3 groups, group I as control (K-0) was given 1.0 ml distilled water/rabbit orally, group II (K-10) was infected with single dose of 10x10<sup>6</sup> oocysts of <em>E. magna</em>/rabbit orally, and group III (K-20) was infected with single dose of 20x10<sup>6</sup> oocysts of <em>E. </em><em>magna</em>/rabbit orally. After infection, rabbits were examined for clinical signs, body weight and temperature daily for five days. Blood samples were drawn from the <em>vena marginalis</em> to examine the number of erythrocytes, hemoglobine, packed cell volume (PCV), leukocytes and its deferent, total protein plasma (TPP) and fibrinogen, activities of alkaline phosphatase (ALP), alanine amino transferase (ALT), and aspartat aminotransferase<strong> </strong>(AST). The data were statistically analyzed by two-way anova using factorial design. The results of this research showed that the infection of <em>E.</em><em> magna</em> in rabbits caused fever and weight loss, accompanied by normochromic microcytic anemia (at doses of 10x10<sup>6</sup> oocysts), macrocytic normochromic (at doses of 20x10<sup>6</sup> oocysts), leukocytosis, lymphocytosis, hiperfibrinogenemia, and increased of ALP activity. There were correlations between clinical symptoms and blood profile of rabbits infected with <em>E.</em><em> magna</em> for five days. The higher the dose and the longer the infection of <em>E.</em><em> magna</em> in rabbits caused weight loss, increased body temperature, MCV (microcytic to macrocytic), leukocyte, fibrinogen and ALP activity. These findings were useful to have a better understanding of pathophysiology of <em>E. magna </em>infection<em> </em>inĀ  rabbits.</p><p><strong>Key Words</strong>: <em>Eimeria</em><em> magna</em>, oocyst, rabbit, blood profile</p><p>A Hana et al/Animal Production 13(3):185-190 (2011)</p>
Publication, Distribution, Etc. Faculty of Animal Science, Jenderal Soedirman University
2012-03-07 00:00:00
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Data Source Entry ANIMAL PRODUCTION; Vol 13, No 3 (2011): ANIMAL PRODUCTION
Language Note en
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